The Complementarity Plot (CP)

developed at:
Crystallography and Molecular Bilogy Division,
Biophysics Division
Saha Institute of Nuclear Physics

Users reporting results using the Complementarity Plot should cite the following articles:

1. Self-Complementarity within Proteins: Bridging the Gap between Binding and Folding
Sankar Basu, Dhananjay Bhattacharyya, and Rahul Banerjee*
Biophysical Journal, 2012, 102 (11) : 2605-2614
(pdf)

2. SARAMA: A Standalone Suite of Programs for the Complementarity Plot
A Graphical Structure Validation Tool for Proteins

Sankar Basu*, Dhananjay Bhattacharyya, and Rahul Banerjee*
Journal of Bioinformatics and Intelligent Control, 2013, 2 (4) : 321-323
(pdf)

3. Applications of the complementarity plot in error detection and structure validation of proteins
Sankar Basu, Dhananjay Bhattacharyya, and Rahul Banerjee*
Indian Journal of Biochemistry and Biophysics, 2014, 51 (June) : 188-200
(pdf)
(Supplementary Materials)

4. SARAMAint: The Complementarity Plot for Protein–Protein Interface
Sankar Basu, Dhananjay Bhattacharyya, and Bjorn Wallner*
Journal of Bioinformatics and Intelligent Control, 2014, 3 (December) : 309-314
(pdf)

Principal Correspondence: Rahul Banerjee (rahul.banerjee[AT]saha.ac.in)

Send your queries, suggestions or Bugg-reports to: Sankar Basu (nemo8130[AT]gmail.com, sankar.basu[AT]liu.se)

Download:

  • SARAMA: Complementarity Plots for Globular Protein Interiors (LINUX)
  • Multidielectric version
  • Redirect to GitHub


  • SARAMAint: Complementarity Plots for Protein-Protein Interface (LINUX)
  • Multidielectric version
  • Redirect to GitHub
  • Redirect to IFM Bioinformatics, Linkoping University, Sweden


  • The Multi Dielectric version(s) of both SARAMA and SARAMAint uses the Smooth Gaussian Dielectric Function of Delphi v.6.2 to model the internal dielectric of the protein interior / interface
  • Documentation:

    README