Basepairs involving Hoogsteen edge of Guanine and WatsonCrick edge of Uracil

Basepairs involving Hoogsteen(H) edge of Guanine and WatsonCrick(W) edge of Uracil is shown. Highlighted examples are found from RNA crystal structures obtained from PDB.

Base pairs stabilized by C-H...N/O interactions along with N-H...N/O hydrogen bonds

Basepair (type & Orientation)	*Frequency	Example	Hydrogen bonding atoms with their precursors
G:U h:w Cis	9/ 1	Optimized Model Structure	C4-N7...N3-C6 N9-C8...O2-N1
G:U h:w Trans	2	Optimized Model Structure	C5-N7...N3-C6 C4-C8...O4-C5

Basepair

(type & Orientation)

*Frequency

Example

Hydrogen bonding atoms with their precursors

G:U h:w Cis

9/
1

Optimized Model Structure

C4-N7...N3-C6

N9-C8...O2-N1

G:U h:w Trans

Optimized Model Structure

C5-N7...N3-C6

C4-C8...O4-C5